Disease: Malignant Neoplasms
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
SLC5A5 Q92911 solute carrier family 5 member 5 Transporter 2.9E-03 0.499 0.769
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
OCLN Q16625 occludin 8.6E-07 0.507 0.846
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FASN P49327 fatty acid synthase Enzyme 1.00 0.474 0.846
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923